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马赛克移植术修复膝关节软骨损伤的临床疗效分析
To analyze the clinical effect of OATs in repairing knee cartilage injury
投稿时间:2024-09-24  
DOI:10.3969/j.issn.1672-5972.2025.03.004
中文关键词:  软骨损伤  软骨修复  马赛克移植  保膝治疗
英文关键词:Cartilage injury  Cartilage repair  OATs  Knee salvage treatment
基金项目:
作者单位邮编
NGUYEN DUC QUI* 武汉大学人民医院运动医学与关节外科湖北 武汉430060 430060
何雄威* 武汉大学人民医院运动医学与关节外科湖北 武汉430060 430060
李皓桓* 武汉大学人民医院运动医学与关节外科湖北 武汉430060 430060
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中文摘要:
      目的 评估马赛克移植术(osteochondral autograft transplantation surgery, OATs)修复膝关节软骨损伤的临床疗效,并探讨其在保膝治疗中的作用。方法 回顾性分析2017年6月至2023年9月于武汉大学人民医院接受马赛克移植术治疗的20例膝关节软骨损伤患者,通过比较患者术前与术后3、6、12个月的关节功能评分(Lysholm评分、VAS评分)、影像学检查等指标,分析软骨修复效果及并发症发生情况,评估其术后临床疗效。结果 共纳入20例患者,随访时间为12 ~ 16个月,平均(14.00±1.89)个月。20例患者Lysholm评分较术前显著提高(P<0.05),VAS评分显著下降(P<0.05),影像学检查显示软骨修复良好。随访过程中,4例患者出现术后并发症,经过对症治疗后恢复良好,未出现长期不良影响。结论 马赛克移植术在修复关节软骨损伤中具有良好疗效,能够显著改善患者的关节功能并减轻疼痛;术后影像学检查显示软骨修复效果理想。OATs是一种安全且有效的治疗方法,适用于关节软骨损伤的患者,值得在临床上进一步推广和应用。
英文摘要:
      Objective To evaluate the clinical efficacy of mosaic autograft transplantation surgery (OATs) in the repair of knee cartilage injury, and to explore its role in knee salvage treatment.Methods Twenty patients with knee cartilage injury who underwent OATs at the People's Hospital of Wuhan University from June 2017 to September 2023 were selected. The joint function scores (Lysholm score, VAS score) and imaging examinations were compared before and 3 months, 6 months and 12 months after operation. The cartilage repair effect and complications were analyzed, and the postoperative clinical efficacy was evaluated.Results A total of 20 patients were enrolled and followed up for 12 to 16 months, with an average of (14.00±1.89) months. The results showed that the Lysholm score of 20 patients was significantly higher than that before operation (P<0.05), the VAS score was significantly lower than that before operation (P<0.05), and the imaging examination showed that the cartilage repair was good. During the follow-up, 4 patients had postoperative complications, and recovered well after symptomatic treatment without long-term adverse effects.Conclusion OATs has a good effect in repairing articular cartilage injury, which can significantly improve the joint function and relieve pain. Postoperative imaging examination showed that the cartilage repair effect was ideal. In conclusion, OATs is a safe and effective treatment for patients with articular cartilage injury, which is worthy of further promotion and application in clinical practice.
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