| Graphene material is a new two-dimensional carbon material, getting more and more attention in the biosensing, tumor diagnosis, drug and gene carrier, antibacterial and anti-virus, tissue engineering and other biomedical applications. At the same time, graphene material can promote stem cell proliferation and osteogenic differentiation, have abilities of antibacterial and drug controlled-release, which becomes a promising orthopedic biomaterials. This review summarizes the recent advances of application of graphene material in the field of orthopedic materials, and discusses the related cellular and molecular mechanisms, which is expected to provide useful information for basic and clinical research in future. |
