Objective To investigate the effect of two kinds of TLIF scheme including open and minimally invasive on perioperative clinical parameters, ODI score and postoperative complications of patients with single segment lumbar degenerative disease. Methods 140 patients with single segment lumbar degenerative disease were chosen in the period from Aug 2011 to May 2014 in our hospital and randomly divided into two groups including open group (70 patients) with open TLIF scheme and minimally invasive group (70 patients) with minimally invasive TLIF scheme; and the perioperative clinical index, VAS score, JOA score and ODI score before and in 3 months,12 months 24 months after surgery, interbody fusion rate and postoperative complications incidence after operation of both groups were compared. Results There was no significant difference in operation time between two groups (P<0.05). The intraoperative blood loss, postoperative blood loss and the time of postoperative activity for first time of minimally invasive group was significant higher than open group(P<0.05). The VAS scores, JOA scores and ODI scores in 3 months after operation of minimally invasive group were significant better than open group and before operation(P<0.05). There was no significant difference in the VAS scores, JOA scores and ODI scores in 12 and 24 months after operation between 2 groups (P<0.05). The interbody fusion rate after operation of minimally invasive group were significant higher than open group(P<0.05). There was no significant difference in the postoperative complications incidence after operation between 2 groups(P<0.05). Conclusion Minimally invasive TLIF scheme in the treatment of patients with single segment lumbar degenerative disease possess the advantages including smaller surgical trauma and shorter postoperative recovery time and can efficiently rapidly relieve the pain of leg and waist, improve the limb function, and not increase the risk of complications after operation. |