Objective To analyze the recurrence and risk factors of single-center giant cell tumor of bone in Xinjiang after surgery.Methods The clinical data of 75 patients with giant cell tumors of bone in Affiliated Tumor Hospital of Xinjiang Medical University from February 2011 to November 2021 were retrospectively analyzed. The relevant factors that may affect postoperative recurrence were included: Sex, age, location, pathological fracture, soft tissue mass, Campanacci grade, different surgical methods, and tumor diameter ≥ 4 cm. Univariate and multivariate analysis of risk factors for postoperative recurrence of giant cell tumor of bone were conducted.Results Among the 75 patients with giant cell tumor of bone, the male to female ratio was 0.83∶1. The peak incidence was between 30 and 39 years old. There were 14 patients with postoperative recurrence, the recurrence time was 6-49 months, and the recurrence rate was 18.7%. Campanacci grade, different surgical methods, and tumor length ≥ 4 cm were significantly correlated with the recurrence of giant cell tumor of bone. Multivariate Cox analysis showed that tumor length ≥ 4 cm was an independent risk factor for postoperative recurrence of giant cell tumor of bone.Conclusion Campanacci grade, different surgical methods, and tumor length ≥ 4 cm are closely related to postoperative recurrence of giant cell tumor of bone. Tumor length ≥ 4 cm is an independent risk factor for postoperative recurrence of giant cell tumor of bone. Clinically, we should strictly grasp the indications of different operations to avoid postoperative recurrence. |